The 828mkII-USB provides a high-speed "ultra-fast" (480 Mbit) USB 2.0 connection to any USB 2.0-equipped Mac or PC. Users can freely choose between purchasing the 828mkII FireWire model or the USB 2.0 model, depending their computer and other FireWire or USB devices they plan to connect to it. Most recent computers (built within the last several years) support the high-speed USB 2.0 standard.

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